REGIS INTERNATIONAL MONTESSORI SCHOOLWEEK 1: THE DIGESTIVE SYSTEM I - STRUCTURE AND MACRONUTRIENT JOURNEY
This is the involuntary, wave-like contraction of the smooth muscles in the alimentary canal wall that propels the bolus forward. It is so effective it works even against gravity.
|
Location |
Gland/Source |
Enzyme |
Substrate |
Products |
Optimal pH & Notes |
|
Mouth |
Salivary Glands |
Salivary Amylase |
Starch (Polysaccharide) |
Maltose (Disaccharide) |
Neutral (6.7- 7.0). Denatured by stomach acid. |
|
Stomach |
Gastric Glands |
Pepsin |
Proteins |
Peptides (shorter chains) |
Acidic (1.5-2.5). Secreted as inactive pepsinogen to avoid self-digestion. |
|
Location |
Gland/Source |
Enzyme |
Substrate |
Products |
Optimal pH & Notes |
|
Stomach (Infants) |
Gastric Glands |
Rennin |
Soluble Caseinogen |
Insoluble Casein (curd) |
Acidic. Slows the passage of milk for better protein digestion. |
|
Duodenum |
Pancreas |
Pancreatic Amylase |
Starch |
Maltose |
Alkaline (8.0). Continues carbohydrate digestion. |
|
Duodenum |
Pancreas |
Trypsin |
Proteins/Peptides |
Shorter Polypeptides |
Alkaline. Secreted as inactive trypsinogen, activated by an intestinal enzyme. |
|
Duodenum |
Pancreas |
Lipase |
Emulsified Fats |
Fatty Acids + Glycerol |
Alkaline. Requires bile for emulsification to be effective. |
|
Ileum |
Intestinal Glands |
Maltase |
Maltose |
Glucose + Glucose |
Alkaline. These "brush border" enzymes complete digestion. |
|
Location |
Gland/Source |
Enzyme |
Substrate |
Products |
Optimal pH & Notes |
|
Ileum |
Intestinal Glands |
Sucrase |
Sucrose |
Glucose + Fructose |
Alkaline. |
|
Ileum |
Intestinal Glands |
Lactase |
Lactose |
Glucose + Galactose |
Alkaline. Lactose intolerance results from lactase deficiency. |
|
Ileum |
Intestinal Glands |
Peptidases (Erepsin) |
Polypeptides/Pep tides |
Amino Acids |
Alkaline. The final step in protein digestion. |
the cell, causing it to swell and potentially burst (lysis).
|
Feature |
Diffusion |
Osmosis |
Active Transport |
|
Substance Moved |
Any particle (solutes, gases) |
Water molecules only |
Specific ions/molecules (e.g., Na⁺, K⁺, glucose) |
|
Concentration Gradient |
Down the gradient (High → Low) |
Down the water potential gradient |
Against the gradient (Low → High) |
|
Feature |
Diffusion |
Osmosis |
Active Transport |
|
Membrane Requirement |
No (but can occur across one) |
Yes (Selectively Permeable) |
Yes (with Carrier Proteins) |
|
Energy (ATP) Requirement |
No (Passive) |
No (Passive) |
Yes (Active) |
|
Saturation Kinetics |
No (rate proportional to gradient) |
No |
Yes (limited by number of carrier proteins) |
the body. This separates oxygenated and deoxygenated blood and creates two distinct circuits:
|
Feature |
Artery |
Capillary |
Vein |
|
Function |
Carry blood away from heart |
Site of exchange with tissues |
Carry blood towards heart |
|
Wall Structure |
Thick, muscular, elastic |
Very thin (one cell thick) |
Thin, less muscular |
|
Lumen Diameter |
Narrow |
Microscopic (one RBC wide) |
Wide |
|
Blood Pressure |
High |
Drops significantly |
Low |
|
Valves |
Absent (except aorta/pulmonary) |
Absent |
Present (prevent backflow) |
|
Blood Carried |
Oxygenated (except Pulmonary) |
Mixed (O₂ delivered, CO₂ collected) |
Deoxygenated (except Pulmonary) |
No nucleus (in mammals), packed with hemoglobin. The biconcave shape maximizes surface area for gas exchange and allows flexibility.
oxyhemoglobin and releases it in the tissues.
coordinated, upward motion to sweep this mucus towards the pharynx, where it is swallowed or expectorated. This is a vital defense mechanism.